Transcranial magnetic stimulation reveals complex cognitive control representations in the rostral frontal cortex
| Autor: | I. Beckmann, Ivo Kuhlemann, Jörg Bahlmann, Achim Schweikard, Thomas F. Münte |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Brain network Analysis of Variance Frontal cortex General Neuroscience medicine.medical_treatment Cognition Neuropsychological Tests Transcranial Magnetic Stimulation Frontal Lobe Transcranial magnetic stimulation Executive Function Young Adult Reaction Time Visual Perception medicine Humans Female Frontal region Control (linguistics) Psychology Neuroscience |
| Zdroj: | Neuroscience. 300:425-431 |
| ISSN: | 0306-4522 |
| DOI: | 10.1016/j.neuroscience.2015.05.058 |
| Popis: | Convergent evidence suggests that the lateral frontal cortex is at the heart of a brain network subserving cognitive control. Recent theories assume a functional segregation along the rostro-caudal axis of the lateral frontal cortex based on differences in the degree of complexity of cognitive control. However, the functional contribution of specific rostral and caudal sub-regions remains elusive. Here we investigate the impact of disrupting rostral and caudal target regions on cognitive control processes, using Transcranial Magnetic Stimulation (TMS). Participants performed three different task-switching conditions that assessed differences in the degree of complexity of cognitive control processes, after temporally disrupting rostral, or caudal target regions, or a control region. Disrupting the rostral lateral frontal region specifically impaired behavioral performance of the most complex task-switching condition, in comparison to the caudal target region and the control region. These novel findings shed light on the neuroanatomical architecture supporting control over goal-directed behavior. |
| Databáze: | OpenAIRE |
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