Copper-catalyzed asymmetric [4+1] cycloadditions of enones with diazo compounds to form dihydrofurans
| Autor: | Sunghee Son, Gregory C. Fu |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
chemistry.chemical_element
Stereoisomerism Biochemistry Medicinal chemistry Catalysis Article chemistry.chemical_compound Bipyridine Colloid and Surface Chemistry Organic chemistry Furans chemistry.chemical_classification Diazonium Compounds Ligand Enantioselective synthesis General Chemistry General Medicine Ketones Copper Combinatorial chemistry chemistry Models Chemical Copper catalyzed Diazo |
| Zdroj: | Journal of the American Chemical Society. 129(5) |
| ISSN: | 0002-7863 |
| Popis: | This report describes the use of a planar-chiral bipyridine ligand to achieve the first diastereo- and enantioselective copper-catalyzed [4+1] cycloadditions of enones with diazo compounds to produce highly substituted 2,3-dihydrofurans. The method is applied to a catalytic asymmetric synthesis of a deoxy-C-nucleoside. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|