Assessment of Left Ventricular Function using a Two-Dimensional Speckle Tracking Echocardiography in Asymptomatic Survivors of Hodgkin’s Lymphoma in Long-Term Follow-Up

Autor: Berrin Umman, Meliha Nalcaci, Mustafa Altinkaynak, Rafet Başar, Nida Oztop, Adem Atici, Pelin Karaca Ozer
Rok vydání: 2021
Předmět:
Zdroj: İstanbul Medical Journal, Vol 22, Iss 4, Pp 300-305 (2021)
ISSN: 2148-094X
2619-9793
Popis: Introduction:Two-dimensional speckle tracking echocardiography (2D-STE) is sensitive in the assessment of left ventricular (LV) systolic function and may aid in diagnosis of late cardiac effects in asymptomatic Hodgkin’s lymphoma (HL) survivors in long-term follow-up.Methods:This is a cross-sectional study of 21 HL survivors previously treated with anthracyclines, with (8/21) or withoutmediastinal (8/21) radiotherapy and no recurrence at least 3 years after treatment compared to age-matched 43 healthy volunteers. To assess long-term cardiac complications, we performed 12-lead electrocardiography and 2D transthoracic echocardiography. In addition to conventional echocardiographic parameters, we used tissue Doppler echocardiography for LV diastolic functions and 2D-STE for evaluating the global longitudinal strain (GLS) of the LV myocardium.Results:The mean age of the HL survivors was 40±15 years and the female sex was predominant (11/21). The average PR interval of the HL survivors was significantly longer (154.7±19.6 ms vs 133.8±13.9 ms, p
Databáze: OpenAIRE