Relationship between chest CT scan findings with SOFA score, CRP, comorbidity, and mortality in ICU patients with COVID‐19
| Autor: | Armin Sadeghi, Aida Malek Mahdavi, Mohammad Esmaeil Hejazi, Zahra Navarbaf, Leila Namvar, Rozhin Moradi, Hamed Valizadeh, Mohammad Kazem Tarzamni |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Organ Dysfunction Scores Comorbidity Overweight Malignancy Ground-glass opacity law.invention law Internal medicine medicine Humans Lung Retrospective Studies Original Paper biology SARS-CoV-2 business.industry C-reactive protein COVID-19 General Medicine medicine.disease Original Papers Intensive care unit Intensive Care Units C-Reactive Protein Heart failure biology.protein SOFA score medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | International Journal of Clinical Practice |
| ISSN: | 1742-1241 1368-5031 |
| DOI: | 10.1111/ijcp.14869 |
| Popis: | Objective This study aimed to investigate the relationship between chest computed tomography (CT) scan findings with sequential organ failure assessment (SOFA) score, C‐reactive protein (CRP), comorbidity, and mortality in intensive care unit (ICU) patients with coronavirus disease 19 (COVID‐19). Method Adult patients (≥18 years old) with COVID‐19 who were consecutively admitted to the Imam‐Reza Hospital, Tabriz, East‐Azerbaijan Province, North‐West of Iran between March 2020 and August 2020 were screened and total of 168 patients were included. Demographic, clinical, and mortality data were gathered. Severity of disease was evaluated using the SOFA score system. CRP levels were measured and chest CT scans were performed. Results Most of patients had multifocal and bilateral ground glass opacity (GGO) pattern in chest CT scan. There were significant correlations between SOFA score on admission with multifocal and bilateral GGO (P = .010 and P = .011, respectively). Significant relationships were observed between unilateral and bilateral GGO patterns with CRP (P = .049 and P = .046, respectively). There was significant relationship between GGO patterns with comorbidities including overweight/obesity, heart failure, cardiovascular diseases, and malignancy (P .05). Conclusion Multifocal bilateral GGO was the most common pattern. Although chest CT scan characteristics were significantly related with SOFA score, CRP, and comorbidity in ICU patients with COVID‐19, a relationship with mortality was not significant. |
| Databáze: | OpenAIRE |
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