Association Safety of Liver Preservation Solutions at the State University of Campinas From 2010 to 2014
| Autor: | C.H.P. Reigada, Cecília Amélia Fazzio Escanhoela, Larissa Bastos Eloy da Costa, T.d.A.P. Mattosinho, E.C. de Ataide, Ilka de Fátima Santana Ferreira Boin |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Organ Preservation Solutions education Liver transplantation Young Adult medicine Preservation solutions Humans Longitudinal Studies Survival rate Liver preservation Aged Retrospective Studies Transplantation business.industry Cold Ischemia Graft Survival Significant difference Patient survival Organ Preservation Odds ratio Middle Aged Confidence interval Liver Transplantation Surgery Survival Rate Liver Female business |
| Zdroj: | Transplantation Proceedings. 49:761-764 |
| ISSN: | 0041-1345 |
| Popis: | The probable reason for mixing solutions during the harvesting procedure is due to the presence of multiple transplant teams that have their own solution usage tradition. Despite numerous studies comparing the efficacy of different preservation solutions, there is no study addressing the associating solution and if there is any impact on liver graft and patient survival. The aim was to evaluate the effect of the association of preservation solutions during the harvesting procedure on liver transplantation outcomes, especially in relation to the degree of preservation injury in the postreperfusion period and patient survival. We analyzed 206 transplants that were distributed as follows: when there was association (89/206 = 43.2%) and when there was no association (117/206 = 56.8%). There was a statistically significant difference in relation to the degree of preservation injury correlated to cold ischemia time ( P = .009, odds ratio 1.992; 95% confidence interval 1.185–3.347). Severe harvesting (grades III and IV) was 71.8% when the solution was not associated ( P = .008). There was no difference regarding patient survival either. We found that the association of liver preservation solutions has no impact on patient survival, so it can be done safely. The best survival rate was associated with minimal harvesting. |
| Databáze: | OpenAIRE |
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