The critical role of mesenchymal stromal/stem cell therapy in COVID‐19 patients: An updated review
| Autor: | Mitra Ayyasi, Golnaz Goodarzi, Sadra Samavarchi Tehrani, Mohsen Ebrahimi, Arghavan Zebardast, mohammad taha saadati rad |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
2019-20 coronavirus outbreak
Stromal cell Coronavirus disease 2019 (COVID-19) medicine.medical_treatment Clinical Biochemistry Review Article Cell Communication Bioinformatics Mesenchymal Stem Cell Transplantation Biochemistry medicine new coronavirus disease 2019 pneumonia Humans Review Articles mesenchymal stem cell business.industry SARS-CoV-2 Mesenchymal stem cell Toll-Like Receptors COVID-19 Mesenchymal Stem Cells Cell Biology General Medicine Stem-cell therapy immunoregulatory medicine.disease Infectious disease (medical specialty) cytokine storm Stem cell Cytokine storm business Cytokine Release Syndrome |
| Zdroj: | Cell Biochemistry and Function |
| ISSN: | 1099-0844 0263-6484 |
| Popis: | New coronavirus disease 2019 (COVID-19), as a pandemic disaster, has drawn the attention of researchers in various fields to discover suitable therapeutic approaches for the management of COVID-19 patients. Currently, there are many worries about the rapid spread of COVID-19; there is no approved treatment for this infectious disease, despite many efforts to develop therapeutic procedures for COVID-19. Emerging evidence shows that mesenchymal stromal/stem cell (MSC) therapy can be a suitable option for the management of COVID-19. These cells have many biological features (including the potential of differentiation, high safety and effectiveness, secretion of trophic factors and immunoregulatory features) that make them suitable for the treatment of various diseases. However, some studies have questioned the positive role of MSC therapy in the treatment of COVID-19. Accordingly, in this paper, we will focus on the therapeutic impacts of MSCs and their critical role in cytokine storm of COVID-19 patients. |
| Databáze: | OpenAIRE |
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