Impact of vitamin D supplementation model on the circulating levels of 25 (OH) D in Algerian children aged 1–23 months
| Autor: | Thierry Dupré, Jean Paul Grangaud, Mustapha Kamel Assami, Cherifa Akrour-Aissou |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Vitamin Endocrinology Diabetes and Metabolism Clinical Biochemistry Physiology Chemoprevention Biochemistry vitamin D deficiency 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Vitamin D and neurology Humans Medicine Vitamin D Molecular Biology Calcifediol Vitamin d supplementation business.industry Infant Newborn Infant Cell Biology Vitamin D Deficiency medicine.disease Treatment Outcome 030104 developmental biology chemistry Algeria 030220 oncology & carcinogenesis Dietary Supplements Vitamin D supplement Molecular Medicine Female business |
| Zdroj: | The Journal of Steroid Biochemistry and Molecular Biology. 196:105487 |
| ISSN: | 0960-0760 |
| Popis: | Vitamin D deficiency is a public health problem around the world. In Algeria, the nutritional situation is still subject to uncertainties. In order to evaluate the vitamin D status and to know the impact of the current vitamin D supplementation model on the circulating levels of 25 (OH) D, an investigation was conducted on a group of Algerian children. The study was conducted in the Blida region (Northern Algeria). Sampling focused on 150 healthy children, aged between 1 and 23 months old, recruited from Ben Boulaid hospital pediatric ward. 83% of children (n = 125) have been supplemented with vitamin D (D3 B.O.N®) according to a scheme currently designed in Algeria (the first intake of 200 000 IU at 1 month and the second intake of 200 000 IU at 6 months). 17% of children (n = 25) have escaped from a supplementation. The average values of 25(OH) D are respectively: 51 ± 20 μg/L for 103 supplement children with vitamin D (25 (OH)D ≤ 100 μg/L), 222 ± 106 μg/L for 22 supplement children with vitamin D (25(OH) D > 100 μg/L) and 30 ± 16 μg/L for 25 non-supplement children with vitamin D. The prevalence of vitamin D deficiency is lower (4%) among the children group with vitamin D supplement. These results show that the vitamin D supplementation model seems entirely efficient on the improvement of vitamin D status. |
| Databáze: | OpenAIRE |
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