Cross motor innervation of the hypoglossal nerve : a pilot study of predictors for successful opening of the soft palate
| Autor: | Clemens Heiser, Olivier M. Vanderveken, Günther Edenharter, Benedikt Hofauer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Hypoglossal Nerve medicine.medical_specialty Neurology Pilot Projects Upper airway stimulation Stimulation Polysomnography 03 medical and health sciences 0302 clinical medicine Tongue Monitoring Intraoperative ENT • Original Article medicine Humans 030223 otorhinolaryngology Motor Neurons medicine.diagnostic_test Soft palate business.industry Middle Aged Hypoglossal nerve stimulation medicine.disease Obstructive sleep apnea Electric Stimulation ddc medicine.anatomical_structure Otorhinolaryngology Anesthesia Female Neurology (clinical) Human medicine Palate Soft Cross motor innervation business Hypoglossal nerve 030217 neurology & neurosurgery |
| Zdroj: | Sleep and breathing Sleep & Breathing = Schlaf & Atmung |
| ISSN: | 1520-9512 |
| Popis: | Purpose Selective hypoglossal nerve stimulation has proven to be a successful treatment option in patients with obstructive sleep apnea. The aim of this pilot study was to investigate if there is a cross-innervation of the hypoglossal nerve in humans and if patients with this phenotype show a different response to hypoglossal nerve stimulation compared to those with ipsilateral-only innervation Methods Nineteen patients who previously received a selective hypoglossal nerve stimulation system (Inspire Medical Systems, Golden Valley, USA) were implanted with a nerve integrity system placing electrodes on both sides of the tongue. Tongue motions were recorded one and two months after surgery from transoral and transnasal views. Polysomnography (PSG) was also performed at two months. Electromyogram (EMG) signals and tongue motions after activation were compared with PSG findings. Results Cross-innervation showed significant correlation with bilateral tongue movement and bilateral tongue base opening, which were associated with better PSG outcomes. Conclusion Cross motor innervation of the hypoglossal nerve occurs in approximately 50% of humans, which is associated with a positive effect on PSG outcomes. Bilateral stimulation of the hypoglossal nerve may be a solution for non-responding patients with pronounced collapse at the soft palate during drug-induced sleep endoscopy. |
| Databáze: | OpenAIRE |
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