Doença de Chagas aguda pós-transfusional sem miocardite
| Autor: | Sogayar R, Evanil Pires de Campos, Izilda Maestá, Cláudia E. O. Pires de Campos, Fernando C. de L. Schmidt |
|---|---|
| Přispěvatelé: | Universidade Estadual Paulista (Unesp) |
| Jazyk: | angličtina |
| Rok vydání: | 1988 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Pathology lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 medicine.medical_treatment Autopsy Gastroenterology Doença de Chagas Transfusional Nephropathy Sepsis Diabetes mellitus Internal medicine medicine Transfusional Chagas Disease Kimmelstiel Wilson business.industry Glomerulosclerosis medicine.disease Nephrectomy Infectious Diseases Benznidazole Kimmelstiel Wilson nephropathy Parasitology business Xenodiagnosis medicine.drug |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 21, Iss 4, Pp 205-208 (1988) SciELO Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1678-9849 0037-8682 |
| Popis: | Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:05:50Z No. of bitstreams: 1 S0037-86821988000400009.pdf: 230891 bytes, checksum: 86d48f621d7d4b84425b1ffa48690284 (MD5) Made available in DSpace on 2013-08-22T19:05:50Z (GMT). No. of bitstreams: 1 S0037-86821988000400009.pdf: 230891 bytes, checksum: 86d48f621d7d4b84425b1ffa48690284 (MD5) Previous issue date: 1988-12-01 Made available in DSpace on 2013-09-30T20:09:46Z (GMT). No. of bitstreams: 1 S0037-86821988000400009.pdf: 230891 bytes, checksum: 86d48f621d7d4b84425b1ffa48690284 (MD5) Previous issue date: 1988-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T15:17:46Z No. of bitstreams: 1 S0037-86821988000400009.pdf: 230891 bytes, checksum: 86d48f621d7d4b84425b1ffa48690284 (MD5) Made available in DSpace on 2014-05-20T15:17:46Z (GMT). No. of bitstreams: 1 S0037-86821988000400009.pdf: 230891 bytes, checksum: 86d48f621d7d4b84425b1ffa48690284 (MD5) Previous issue date: 1988-12-01 Trata-se de paciente do sexo feminino, com 59 anos de idade, procedente de Itaporanga (SP), diabética e nefropata crônica, internada em virtude de surtos de pielonefnte e insuficiência renal aguda. Dentre outras medidas terapêuticas, recebeu transfusão de sangue. Cerca de dois dias após a última transfusão (sangue oriundo de doador, posteriormente identificado como chagásico) encontraram-se formas tripomastigotas de Trypanosoma cruzi em lâmina preparada para execução de hemograma. Iniciou-se tratamento com Benzonidazol. A paciente cursou para, pleuropneumonia e de secreção purulenta cirúrgica isolou-se Klebsiella spp. A septicemia conduziu a paciente ao êxito letal. Nenhuma lesão tecidual foi observada no miocárdio, no sistema nervoso central, adrenal ou nos demais órgãos examinados. D.E. O., a 59 years old white female bom in Paranagua (PR), came from Itaporanga with Kimmelstiel Wilson nephropathy diabetes and pyelonephritis with acute renal failure followed by a nephrectomy. Anaemia and malnutrition led to blood transfusions before and after surgery. on the 34th day, she developed high fever, prostration, agressivity with mental confusion, abdominal cramps and diarrhea. Trypanosomes were seen in peripheral blood smears. Haemoculture and xenodiagnosis was positive. A complement fixation test was negative. Benznidazole (6 mg/kg/day) was started. During treatment she presented pulmonary infection and a surgical purulent secretion showed Klebsiella sp. Despite intensive medical care she died of sepsis. Autopsy revealed evidence of diabetes mellitus (glomerulosclerosis, hepatic lesions, pancreatic fibrosis and generalised arteriolar disease). No chagasic lesions were detected in the heart, central nervous system, adrenal or other tissues. Faculdade de Medicina de Botucatu Departamento de Moléstias Infecciosas e Parasitárias, Dermatologia e Radiologia UNESP Instituto de Biociências UNESP Instituto de Biociências |
| Databáze: | OpenAIRE |
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