| Autor: |
Dan Xie, Fang-Jian Zhou, Tie-Bang Kang, Xin-Yuan Guan, Wei Chen, Hai-Liang Liu, Xiao-Han Jin, Jie-Wei Chen, Li-Juan Jiang, Jun Lu, Ri-Xin Chen, Mu-Yan Cai, Yong Feng, Ning-Fang Ma, Gang-Jun Yuan, Song Wu, Jun-Hang Luo, Jia-Xing Zhang, Xin Chen |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22419636.v1 |
| Popis: |
Supplementary Figure S1. Identification of 3'UTR shortening of RALA and RAC1 from UCB, colorectal carcinoma, hepatocellular carcinoma and non-small cell lung cancer samples. Supplementary Figure S2. RAC1 with short 3'UTR promotes tumorigenesis and produces more protein due to evasion of miRNA-mediated repression. Supplementary Figure S3. Screening of APA factors that contribute to the PAS selection of RAC1 in UCB. Supplementary Figure S4. CSTF2 regulates colony formation and invasiveness abilities of shorter RAC1 isoform in UCB. Supplementary Table S1. PDUI value calculated from DaPars analysis of 15 pairs of UCB and adjacent normal bladder tissues. Supplementary Table S2. KEGG pathway analyses of APA genes identified from RNA-Seq. Supplementary Table S3. RAC1 genomic mutations identified from TCGA UCB database. Supplementary Table S4. Correlation between the expression of CSTF2 and clinicopathologic characteristics of UCB patients |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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