Therapeutic mild hypothermia improves outcome after out-of-hospital cardiac arrest
| Autor: | A. W. J. van ’t Hof, E. Oosterloo, J.H.E. Dambrink, W. Dekker, I. Andrade Ferreira, M. Schutte, B. W. Mooi |
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| Rok vydání: | 2009 |
| Předmět: |
Fibrillation
Coma medicine.medical_specialty Resuscitation business.industry medicine.disease Intensive care unit law.invention Surgery law Anesthesia Pulseless electrical activity Conventional PCI Ventricular fibrillation medicine Original Article Asystole medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Netherlands Heart Journal. 17:378-384 |
| ISSN: | 1876-6250 1568-5888 |
| DOI: | 10.1007/bf03086288 |
| Popis: | Purpose. Therapeutic mild hypothermia (TMH) is indicated for comatose survivors of an out-ofhospital cardiac arrest (OHCA) to improve general outcome. Although widely used, there are not many reports on its use on a critical care unit (CCU) or on the comparison of cooling methods.Methods. In a retrospective analysis covering January 2005 to December 2006, 75 consecutive comatose subjects post-OHCA due to ventricular fibrillation and nonventricular fibrillation rhythms (asystole/pulseless electrical activity) were studied in a single tertiary PCI centre. Subjects treated with conventional post-resuscitation care without TMH served as controls (n=26; Jan 2005-Sep 2005). Outcome from controls at hospital discharge was compared with subjects treated with TMH (n=49; Oct 2005-Dec 2006). During the study period, TMH was induced by either external (n=25; Oct 2005-Feb 2006) or endovascular (n=24; Mar 2006-Dec 2006) approach.Results. Besides more females in the control group, there were no major differences in baseline characteristics present between all groups. TMH improved survival (OR 0.36 [0.13-0.95], p |
| Databáze: | OpenAIRE |
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