Post Cardiotomy Extra Corporeal Membrane Oxygenation: Australian Cohort Review
| Autor: | James Farag, Silvana Marasco, Christopher M. Reid, Jenni Williams-Spence, Robyn Summerhayes, Michael Bailey, Rong Shen |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Heart Diseases medicine.medical_treatment 030204 cardiovascular system & hematology Logistic regression Extracorporeal 03 medical and health sciences Extracorporeal Membrane Oxygenation 0302 clinical medicine medicine Extracorporeal membrane oxygenation Humans 030212 general & internal medicine Cardiac Surgical Procedures Retrospective Studies business.industry Australia Retrospective cohort study Oxygenation Middle Aged Prognosis Cardiac surgery Emergency medicine Cohort Female Morbidity Cardiology and Cardiovascular Medicine Cardiotomy business New Zealand |
| Zdroj: | Heart, Lung and Circulation. 29:1865-1872 |
| ISSN: | 1443-9506 |
| DOI: | 10.1016/j.hlc.2020.05.092 |
| Popis: | Background Over the last two decades, technological advancements in the delivery of extra corporeal membrane oxygenation (ECMO) have seen its use broaden and results improve. However, in the post cardiotomy ECMO patient group, survival remains very poor without significant improvements over the last two decades. Our study aims to report on the Australian experience, with the intention of providing background data for the formation of guidelines in the future. Methods Retrospective analysis of prospectively collected data from the Australian and New Zealand Society of Cardiothoracic Surgeons (ANZSCTS) Database was performed. The ANZSCTS database captures at least 60% of cardiac surgical data in Australia, annually. Data was collected on adult patients who received ECMO post cardiotomy from September 2016 to November 2017 inclusive. Transplant and primary cardiomyopathy patients were excluded. Results Of the 16,605 adult patients undergoing cardiac surgery in the 15-month period of the study, 87 patients required post cardiotomy ECMO (0.52%). The average age of the entire cohort was 56 years. Overall survival to discharge was 43.7% (n=38). Multivariable logistic regression analysis demonstrated that multiorgan failure (MOF), increasing age and longer cardiopulmonary bypass time were significant predictors of in hospital mortality. Conclusions Post cardiotomy ECMO support is an uncommon condition. Survival in this study appears to be better than historical reports. Identification of poor prognostic indicators in this study may help inform the development of guidelines for the most appropriate use of this support modality. |
| Databáze: | OpenAIRE |
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