Value of Ultrasound Elastography in the Differential Diagnosis of Cervical Lymph Nodes: A Comparative Study With B-mode and Color Doppler Sonography
Autor: | Leyla Acu, Suna Özhan Oktar, Süleyman Cebeci, Rusen Acu, Cem Yücel |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty genetic structures Adolescent Sensitivity and Specificity 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences Young Adult 0302 clinical medicine Vascularity medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Ultrasonography Doppler Color Child Lymph node Lymphatic Diseases Aged Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Echogenicity Reproducibility of Results Middle Aged medicine.anatomical_structure Cervical lymph nodes 030220 oncology & carcinogenesis Child Preschool Elasticity Imaging Techniques Female Lymph Microcalcification Elastography Radiology Lymph Nodes Differential diagnosis medicine.symptom business Neck |
Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 35(11) |
ISSN: | 1550-9613 |
Popis: | OBJECTIVES The purpose of this study was to determine the usefulness of ultrasound elastography in the evaluation of enlarged cervical lymph nodes in comparison with B-mode and color Doppler sonography. METHODS A total of 220 lymph nodes in 168 consecutive patients who were referred for sonography of the neck were included in this study. B-mode sonograms were evaluated according to short-axis diameter, long-to-short-axis ratio, hilum, echogenicity, and microcalcification. For color Doppler sonography, 5 different patterns were defined according to vascularity. Elastographic patterns of the lesions were categorized to 5 main types. The mean strain index values were calculated for all lymph nodes. Histopathologic findings, clinical and laboratory data, and imaging findings were used as reference standards for the diagnosis of benign and malignant lymph nodes. RESULTS Of the 220 lymph nodes, 69.5% were diagnosed as benign, and 30.5% were diagnosed as malignant. The sensitivity, specificity, and accuracy of B-mode sonography were 97.0%, 31.4%, and 51.3%, respectively; the values were 76.1%, 82.4%, and 80.5% for color Doppler sonography and 82.1%, 56.2%, and 64.1% for elastography. The strain index cutoff value for the differentiation of benign and malignant lymph nodes was accepted as 1.7. The sensitivity, specificity, and accuracy of the strain index were 71.6%, 76.5%, and 75.0%. CONCLUSIONS Ultrasound elastography adds no additional value to combined B-mode and color Doppler sonography for differentiation of benign and malignant cervical lymph nodes. |
Databáze: | OpenAIRE |
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