Effects of HIV infection and/or malaria on maternal and neonatal health in a high‐prevalence setting

Autor: Nieves, Jaén-Sánchez, Gloria, González-Azpeitia, Cristina, Carranza-Rodriguez, Anselmo Joaquim, Muianganisso, Laura Vallejo, Torres, José Luis, Pérez-Arellano
Rok vydání: 2023
Předmět:
Zdroj: Tropical Medicine & International Health. 28:98-106
ISSN: 1365-3156
1360-2276
Popis: HIV infection and malaria have been associated with different complications during pregnancy and delivery. HIV-positive pregnant women are at increased risk for all adverse outcomes of malaria during pregnancy. The main objective was to analyze the obstetric and perinatal consequences of malaria, HIV infection and HIV/malaria coinfection in pregnant women and newborns, which has been less well evaluated.A cross-sectional study was carried out in the Maternity Service of the Provincial Hospital of Tete Mozambique, involving completion of a structured questionnaire that included demographic data, and information on the current pregnancy, delivery and the newborn. In total 819 women (13 to 45 years old) in the immediate postpartum period were enrolled between 1 March and 31 October 2016.The overall prevalence of HIV and malaria, considered separately, in pregnant women was approximately 12% (103 women with HIV and 101 with malaria). Only one-fifth of HIV-infected women knew their HIV status before pregnancy. A significantly higher proportion of women with HIV attended 4 or more antenatal care visits than women without HIV. Caesarean section was less frequent in HIV patients, and peripartum urinary infection was more frequent than in seronegative women [13/103 (12,6%) vs 34/716 (4,7%)]. HIV/malaria coinfection was 17/819 (2%) and was significantly associated with the development of preeclampsia when HIV-infected patients received antiretroviral treatment, and with an increase in urinary tract infections around delivery. With respect to the newborn, coinfection increased the frequency of early neonatal death, as well as neonatal asphyxia and jaundice.In Mozambique, the prevalence of malaria and HIV infection in women of childbearing age continues to be high and contributes additively to complications during pregnancy and childbirth, and in the newborn. Therefore, integrating HIV, malaria and reproductive health services is essential if maternal and fetal outcomes are to improve. This article is protected by copyright. All rights reserved.
Databáze: OpenAIRE
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