Pathogens Causing Diabetic Foot Infection and the Reliability of the Superficial Culture
| Autor: | Mika Helminen, Ilkka Kaartinen, Miska Laakso, Matti Karppelin, Juha Kiiski |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Staphylococcus aureus medicine.medical_specialty Microbiological culture Population medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus Diabetes Mellitus Humans Medicine 030212 general & internal medicine education Retrospective Studies 0303 health sciences education.field_of_study 030306 microbiology business.industry Osteomyelitis Reproducibility of Results Retrospective cohort study Staphylococcal Infections medicine.disease Diabetic foot Diabetic Foot Anti-Bacterial Agents Infectious Diseases Bacteremia Surgery business |
| Zdroj: | Surgical Infections. 22:334-339 |
| ISSN: | 1557-8674 1096-2964 |
| DOI: | 10.1089/sur.2020.072 |
| Popis: | Background: Diabetic foot infection (DFI) is a severe complication of diabetes and a leading cause of hospitalization in the population with diabetes. Empirical intravenous antibiotic agents are initiated according to guidelines based on previously published data on typical pathogens. Therefore, regular evaluation of the pathogens in DFI and their resistance is important to validate current therapies. We evaluated the most current data on bacterial cultures in patients treated at our hospital for DFI and the resistance to the most common antibiotic agents, as well as the reliability of superficial cultures compared with deep tissue cultures. Patients and Methods: This retrospective study was performed at the University Hospital of Tampere and comprised 325 patients with 405 hospitalizations for DFI during the years 2010-2014. Results: The most frequent pathogens in superficial and deep samples were Staphylococcus aureus (36.9%), gram-negative bacilli (24.6%), and β-hemolytic streptococci (BHS, 19.5%). Septicemia was caused most often by Staphylococcus aureus and BHS (34.6% each). The specificity of superficial culture was 91.8%-92.8% and sensitivity 66.7%-87.5%. Conclusions: This study indicates the need to cover Staphylococcus aureus, BHS, and gram-negative bacilli when treating DFI. The reliability of superficial culture was surprisingly good. |
| Databáze: | OpenAIRE |
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