Re-evaluation of ivermectin efficacy against equine gastrointestinal parasites
| Autor: | Steffen Rehbein, W.K Langholff, Dennis D. French, M. R. Chapman, P Hanson, Thomas R. Klei, Martin Visser |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Veterinary medicine Gastrointestinal Diseases Parasitic Diseases Animal ved/biology.organism_classification_rank.species Antiprotozoal Agents Craterostomum acuticaudatum Administration Oral Feces Ivermectin parasitic diseases medicine Animals Horses Parasite Egg Count Larva General Veterinary biology Poteriostomum ved/biology Parascaris equorum General Medicine biology.organism_classification Gastrointestinal parasites Habronema Parasitology Female Horse Diseases Digestive System medicine.drug |
| Zdroj: | Veterinary parasitology. 98(4) |
| ISSN: | 0304-4017 |
| Popis: | Two trials were conducted to confirm the efficacy of ivermectin paste against endoparasites of horses. In these trials, 20 ponies were treated with ivermectin oral paste at 200 mcg kg body weight once on Day 0, and 20 ponies served as unmedicated controls. The animals carried naturally acquired parasite infections as confirmed by pretrial fecal examination. The animals were necropsied for worm recovery on Days 14, 15 or 16. Parasites recovered were identified to species. Horses treated with ivermectin had significantly ( P 99.0% reduction) adult small strongyles ( Coronocyclus spp including C. coronatus , C. labiatus , C. labratus ; Cyathostomum spp including C. catinatum , C. pateratum ; Cylicocyclus spp including C . ashworthi , C. elongatus , C. insigne , C. leptostomum , C. nassatus , C. radiatus ; Cylicodontophorus bicoronatus ; Cylicostephanus spp including C. asymetricus , C. bidentatus , C. calicatus , C. goldi , C. longibursatus , C. minutus ; Gyalocephalus capitatus ; Parapoteriostomum spp including P. euproctus , P. mettami ; Petrovinema poculatum ; Poteriostomum spp including P. imparidentatum , P. ratzii ) and adult large strongyles ( Strongylus edentatus , S. vulgaris ; Triodontophorus spp including T. brevicauda , T. serratus ; Craterostomum acuticaudatum ) than the controls. Ivermectin was also highly effective (94% to >99%, P Gasterophilus intestinalis larvae, Habronema spp., Oxyuris equi , Parascaris equorum . The data from these two trials confirm that ivermectin paste administered to horses orally at 200 mcg kg −1 continues to be highly effective for treatment and control of a broad range of small and large strongyle species as well as other species of gastrointestinal parasites. |
| Databáze: | OpenAIRE |
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