Hyperthermia – description of a method and a review of clinical applications
| Autor: | Magda Kubaszewska, Adam Chicheł, Marek Kanikowski, Janusz Skowronek |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Hyperthermia
medicine.medical_specialty Cancer Research business.industry heating techniques Cancer Hyperthermia Treatment Thermal therapy medicine.disease hyperthermia clinical applications method of treatment Oncology Radiology Nuclear Medicine and imaging medicine Adjuvant therapy cancer Radiology Nuclear Medicine and imaging Radiology business Thermal dose Radiofrequency energy Body tissue Biomedical engineering |
| Zdroj: | Reports of Practical Oncology & Radiotherapy. 12(5):267-275 |
| ISSN: | 1507-1367 |
| DOI: | 10.1016/s1507-1367(10)60065-x |
| Popis: | Summary The aim of this paper is to give a concise description of hyperthermia and a brief review of its clinical applications. Hyperthermia (HT, thermal therapy) is thought to be one of the cancer therapies and is considered to be an artifi cial way of increasing the body tissue temperature by delivering heat obtained from external sources to destroy cancerous cells or prevent their further growth. The fi rst principles of hyperthermic biology are presented. The phenomena of thermotolerance and radiosensitization are briefl y described, as well as the concept of thermal dose delivered to the tissues. Three main clinical applications of HT are presented. They include local, regional or part-body HT and whole-body HT that deliver heat to localized, advanced or deep-seated and disseminated malignancies, respectively, depending on location, depth and staging of the tumour. Energies used to apply heat to the tumour include microwaves, radiofrequency energy, ultrasound, infrared radiators and different kinds of hot sources (hot water, ferromagnetic seeds, nanoparticles, resistive implants). General indications for each HT subtype and possible combinations of HT with other cancer treatment modalities are presented. Substantially, HT is used as an adjuvant therapy and in such a role it is being evaluated in many clinical randomized trials throughout the scientifi c medical centres. Their fi rst preliminary results are already available, but still time is needed to produce fi rm conclusions and strict indications for hyperthermia treatment. |
| Databáze: | OpenAIRE |
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