In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival
| Autor: | Jennifer T. Blundo, Feng Cao, Amir H Sadrzadeh Rafie, Haichang Wang, Christopher K. Zarins, Joseph C. Wu, Beth L. Pruitt, Oscar J. Abilez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Collagen i
Donor cell Cell Survival Biomedical Engineering Medicine (miscellaneous) Biocompatible Materials Bone Marrow Cells Mice Transgenic Cell Separation Biology Mesenchymal Stem Cell Transplantation Article Biomaterials Mice Tissue engineering Animals Whole Body Imaging Matrigel Mesenchymal stem cell Mesenchymal Stem Cells Cell biology Microscopy Fluorescence Immunology Luminescent Measurements Molecular imaging Stem cell Preclinical imaging |
| Popis: | Therapeutic effects from injection of stem cells are often hampered by acute donor cell death as well as migration away from damaged areas. This is likely due to the fact that injected cells do not have the physical and biochemical cues for ordered engrafment. Here we evaluate 3 common biomatrices (Matrigel, Collagen I, Purmatrix) that has the potential of providing suitable scaffolds needed to enhance stem cell survival. The longitudinal fate of transplanted stem cells was monitored by reporter imaging techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|