Metastatic prostate cancer proven by 18F-FCH PET/CT staging scan in patient with normal PSA but high PSA doubling time
| Autor: | Marina Hodolic, Domenico Rubello, Jure Fettich, Anna Margherita Maffione, Marino Cimitan, Borut Gubina |
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| Rok vydání: | 2013 |
| Předmět: |
Oncology
Male medicine.medical_specialty Fluorine Radioisotopes Choline Prostate cancer Internal medicine Biopsy Medicine Doubling time Humans Radiology Nuclear Medicine and imaging Lymph node PSA Velocity PET-CT medicine.diagnostic_test business.industry Goserelin Prostatic Neoplasms General Medicine Middle Aged Prostate-Specific Antigen medicine.disease medicine.anatomical_structure Lymphatic Metastasis Positron-Emission Tomography Hormonal therapy business Nuclear medicine Tomography X-Ray Computed medicine.drug |
| Zdroj: | Clinical nuclear medicine. 38(9) |
| ISSN: | 1536-0229 |
| Popis: | A 59-year-old man presented with frequent urination. Six months ago, his prostate-specific antigen (PSA) was 1.56 ng/mL; currently it is 3.5 ng/mL (PSA doubling time = 6 months; PSA velocity = 0.19 ng/mL/mo). Biopsy revealed aggressive prostate cancer (Gleason score 5 + 5). Staging with (18)F-fluorocholine PET/CT ((18)F-FCH PET/CT) demonstrated lymph node metastasis. After 6 months of hormonal therapy with goserelin, PSA decreased to 0.38 ng/mL. A (18)F-FCH PET/CT restaging scan demonstrated a global reduction of (18)F-FCH lesion uptake with disappearance of some mediastinal and iliac pelvic lymph node activity. |
| Databáze: | OpenAIRE |
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