New approach to environmental investigation of an explosive legionnaires´ disease outbreak in Spain: early identification of potential risk sources by rapid Legionella spp immunosensing technique
| Autor: | Juan C. Montero, Fernando Cebrián, Pedro J. Fernández |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Legionella 030106 microbiology Attack rate Population Disease Biosensing Techniques Environment lcsh:Infectious and parasitic diseases Disease Outbreaks Legionella pneumophila 03 medical and health sciences Risk Factors Environmental health medicine Environmental Microbiology Humans lcsh:RC109-216 education Aged Disease Reservoirs Immunoassay education.field_of_study biology Transmission (medicine) business.industry Public health Outbreak Manzanares Early detection biology.organism_classification medicine.disease 030104 developmental biology Infectious Diseases Early Diagnosis Spain Legionnaires' disease Public Health Legionnaires' Disease business Water Microbiology Research Article Environmental testing Environmental Monitoring |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-8 (2018) |
| ISSN: | 1471-2334 |
| Popis: | Background An explosive outbreak of Legionnaires’ disease (LD) was identified on 11 December 2015 in Manzanares, Ciudad Real, Spain, and was declared closed by 03 February 2016. The number of declared cases was 593 with 277 confirmed cases so that it can be considered as one of the outbreaks with highest attack rate. This rate could be attributed to the ageing of the population, among others, in addition to various risk factors and habits, and the meteorological conditions (thermal inversion) maintained in this municipality at the time. The Public Health Services succeeded in breaking the bacterial transmission. Several facilities were early identified by microbiological analysis, including a cooling tower and a decorative fountain, as possible infectious sources. Rapid analytical techniques for rapid Legionella detection and the shutdown and preventative closure of positive installations have been considered key elements in the control of this outbreak. Results Rapid microbiological analysis helped to the early identification of potential risk sources in a Legionnaires´ disease outbreak, reducing decision-making processes according to the actual needs of the intervention in public health and shortening the exposure of the population. Conclusions Protocolized and immediate intervention in an outbreak is a crucial issue to reduce their effects on public health. For this, identification and control of the suspicious sources able to disseminate the bacteria and cause the illness is required. Rapid analytical techniques like immunomagnetic separation (IMS) method based on the whole bacterial cell detection are shown as excellent tools to investigate all the potential sources of risk. |
| Databáze: | OpenAIRE |
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