The Effect of Rowson-Parr Virus on the Severity of Malaria in Mice
Autor: | Nina Wedderburn, M. H. Salaman, F. E. G. Cox |
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Rok vydání: | 1974 |
Předmět: |
Plasmodium
Erythrocytes Time Factors Lymphoma Plasmodium berghei Plasmodium vinckei Reticulocytosis Fluorescent Antibody Technique Hemolytic Plaque Technique Spleen Microbiology Antibodies Virus Mice parasitic diseases medicine Animals Mice Inbred BALB C Sheep biology Friend virus biology.organism_classification Haemolysis Virology Malaria Blood medicine.anatomical_structure Antibody Formation Female Gammaretrovirus medicine.symptom |
Zdroj: | Journal of General Microbiology. 85:358-364 |
ISSN: | 0022-1287 |
DOI: | 10.1099/00221287-85-2-358 |
Popis: | Summary: Rowson-Parr virus (RPV), which causes lymphoma in Balb/c mice and also depresses the splenic haemolytic plaque-forming cell response to sheep erythrocytes, greatly exacerbates infections caused by two murine Plasmodium species. One of these, Plasmodium vinckei chabaudi, infects mature erythrocytes and the other, Plasmodium berghei yoelii, infects mainly reticulocytes. Mice infected with RPV and either Plasmodium showed a similar degree of reticulocytosis to those which received the Plasmodium alone. Antiplasmodial antibody was much higher in mice which received Plasmodium alone than in those also infected with RPV. |
Databáze: | OpenAIRE |
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