The Effect of Rowson-Parr Virus on the Severity of Malaria in Mice

Autor: Nina Wedderburn, M. H. Salaman, F. E. G. Cox
Rok vydání: 1974
Předmět:
Zdroj: Journal of General Microbiology. 85:358-364
ISSN: 0022-1287
DOI: 10.1099/00221287-85-2-358
Popis: Summary: Rowson-Parr virus (RPV), which causes lymphoma in Balb/c mice and also depresses the splenic haemolytic plaque-forming cell response to sheep erythrocytes, greatly exacerbates infections caused by two murine Plasmodium species. One of these, Plasmodium vinckei chabaudi, infects mature erythrocytes and the other, Plasmodium berghei yoelii, infects mainly reticulocytes. Mice infected with RPV and either Plasmodium showed a similar degree of reticulocytosis to those which received the Plasmodium alone. Antiplasmodial antibody was much higher in mice which received Plasmodium alone than in those also infected with RPV.
Databáze: OpenAIRE