A cross-sectional multicenter study of cognitive and behavioural features in multiple system atrophy patients of the parkinsonian and cerebellar type
Autor: | Tanya Gurevich, Gregor K. Wenning, M. Balas, Nir Giladi, Giuseppe Meco, Margherita Canesi, B.R. Bloem, Giovanni Pezzoli, Chiara Siri, Rianne A. J. Esselink, Werner Poewe, Margarete Delazer, P. Santacruz, Angelo Antonini, Alfonso Rubino, Susanne Duerr, E. Tolosa, F. Marti |
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Rok vydání: | 2013 |
Předmět: |
Male
medicine.medical_specialty Pediatrics Neurology Neuropathology Anxiety Neuropsychological Tests Atrophy Cognition Parkinsonian Disorders Cerebellum medicine Humans parkinson disease multiple system atrophy neuropsychiatric features cognition Attention Effects of sleep deprivation on cognitive performance Cognitive decline Biological Psychiatry Depression (differential diagnoses) Aged medicine.diagnostic_test Depression Neuropsychological test Middle Aged Multiple System Atrophy medicine.disease Psychiatry and Mental health Cross-Sectional Studies Human Movement & Fatigue [DCN MP - Plasticity and memory NCEBP 10] Disease Progression Female Neurology (clinical) Psychology Neuroscience |
Zdroj: | Journal of Neural Transmission, 120, 4, pp. 613-8 Journal of Neural Transmission, 120, 613-8 |
ISSN: | 0300-9564 |
Popis: | Item does not contain fulltext Imaging and neuropathology studies have demonstrated significant abnormalities not only in subcortical, but also in cortical regions of patients with multiple system atrophy (MSA). This raises the possibility that cognitive dysfunction may contribute to the clinical spectrum of this disorder to a greater extent than it is currently not widely appreciated. In this cross-sectional multicenter study from the European multiple system atrophy study group ( http://www.emsa-sg.org ), we applied an extensive neuropsychological test battery in a series of 61 clinically diagnosed probable MSA patients. The results demonstrated that general cognitive decline as assessed by MMSE was uncommon (2 out of 61 patients |
Databáze: | OpenAIRE |
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