Glioblastoma multiforme as initial internal malignancy in Muir-Torre syndrome (MTS)
| Autor: | Neel B. Patel, Michael D. Lehrer, David J Glembocki, Henry T. Lynch |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Keratoacanthoma
Pathology medicine.medical_specialty sebaceous carcinoma MLH Population Case Report MMR mismatch repair Dermatology macromolecular substances CNS central nervous system MSH-2 Sebaceoma familial cancer Sebaceous adenoma glioblastoma multiforme Muir–Torre syndrome sebaceoma Medicine Basal cell carcinoma education education.field_of_study business.industry Muir-Torre syndrome medicine.disease Lynch syndrome mismatch repair hereditary cancer MTS Muir-Torre syndrome business IHC immunohistochemistry Sebaceous carcinoma |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| DOI: | 10.1016/j.jdcr.2015.08.011 |
| Popis: | Muir-Torre syndrome (MTS) is an autosomal-dominant variant of Lynch hereditary cancer syndrome. MTS is defined by sebaceous neoplasms occurring in association with 1 or more internal malignancies.1 The sebaceous neoplasms that characterize MTS are rare among the general population and include sebaceous adenoma, sebaceoma, sebaceous carcinoma, keratoacanthoma with sebaceous differentiation, and basal cell carcinoma with sebaceous differentiation.2 A recent case series described several central nervous system (CNS) malignancies associated with MTS occurring after the development of colon cancer.3 We report a case of MTS with glioblastoma multiforme as the initial internal malignancy. |
| Databáze: | OpenAIRE |
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