Reply to Liu: Amino acid 104 asparagine/glutamic acid of p53 is an adaptively selected site for extreme environments in mammals of the Tibet plateau
| Autor: | Hu-Yue Zu, Sheng-Ting Zhang, Min Li, Yu Liu, Yi-Bin Cao, Chung-I Wu, Yang Zhao, Ming-Yang Wang, Xue-Qun Chen, Xiao-Cheng Chen, Ji-Long Ren, Ji-Zeng Du, Eviatar Nevo |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
Multidisciplinary Ecology Arvicolinae Apoptosis Glutamic acid Biology Plateau (mathematics) Adaptation Physiological Amino acid Cold Temperature Evolution Molecular chemistry Evolutionary biology Sequence prediction Stress Physiological Extreme environment Animals Humans Asparagine Letters Tumor Suppressor Protein p53 Hypoxia |
| Popis: | In our paper, we substantiate the fact that codon 104 variation is adaptive in highland Tibet plateau mammals (1). Liu’s letter (2) claims that codon 104 is not adaptive, which is only based on searching the sequence prediction in National Center for Biotechnology Information (NCBI) without experimental evidence. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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