Heterotopic ossification after hip arthroplasty:A randomized double-blind multicenter study of tenoxicam in 147 hips

Autor: Michael Crawford, Jens Sletgård, Antero Hänninen, Peter Gebuhr, Kjell Keisu, Jesper Dalsgård, Michael Soelberg
Rok vydání: 1996
Předmět:
Zdroj: Acta Orthopaedica Scandinavica. 67:29-32
ISSN: 0001-6470
DOI: 10.3109/17453679608995604
Popis: 147 patients due to have a cemented total hip arthroplasty were randomized to 4 groups. They received either tenoxicam 20 mg or 40 mg, or placebo, for 5 days or morphine on the day of operation and placebo for 4 days. During the first 5 days 14 patients were excluded. The patients were followed for 1 year, during which another 10 patients were excluded. At follow-up, significantly fewer patients had heterotopic ossifications in the tenoxicam groups than in the placebo and morphine groups. There was no significant difference between the 2 tenoxicam-treated groups, and we therefore conclude that tenoxicam 20 mg for 5 days postoperatively can reduce heterotopic ossification after cemented total hip arthroplasty.
Databáze: OpenAIRE