Regional Brain Metabolism During Auditory Hallucinations in Chronic Schizophrenia
| Autor: | Stanley W. Dermer, C. Nahmias, Gregory M. Brown, S Franco, E.S. Garnett, Barbara Szechtman, Henry Szechtman, Ronald D. Kaplan, John M. Cleghorn, P. Cook |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Blood Glucose Psychosis medicine.medical_specialty Hallucinations Posterior parietal cortex Deoxyglucose Audiology 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 medicine Humans Dominance Cerebral Cerebral Cortex Neurons Psychiatric Status Rating Scales Brain Mapping Brain medicine.disease 030227 psychiatry Psychiatry and Mental health Schizophrenia Hallucinating Cingulate region Chronic Disease Auditory Perception Schizophrenic Psychology Chronic schizophrenia Left superior Energy Metabolism Metabolic activity Psychology Neuroscience 030217 neurology & neurosurgery Tomography Emission-Computed |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1472-1465 0007-1250 |
| DOI: | 10.1192/bjp.157.4.562 |
| Popis: | Regions of the brain involved in language and attention were studied using [18F]-fluorodeoxyglucose in PET. In nine chronic DSM–III schizophrenic patients who had persistent auditory hallucinations, ten who had recovered from hallucinations and ten normal controls. In none of the regions examined was metabolic activity significantly different in hallucinating patients compared with that in other groups. However, a pattern of seven significant correlations of metabolic activity between language regions and between frontal and parietal cortex characterised the hallucinating but not the other groups. Three of the seven correlations were significantly greater in hallucinating patients than in the two other groups, and six were greater in hallucinating patients than controls. Metabolism in Broca's region and its right-hemisphere homologue correlated positively and significantly in the hallucinating group, as it did in anterior cingulate and left superior temporal areas, and in right frontal and parietal areas. Hallucination ratings correlated with metabolism in the anterior cingulate region. |
| Databáze: | OpenAIRE |
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