Synchronous Pancreatic Serous Cystic Neoplasm and Duodenal Neuroendocrine Tumor: Case Report and Review of the Literature

Autor: Ann Brinch Madelung, Sönke Detlefsen
Rok vydání: 2018
Předmět:
medicine.medical_specialty
Duodenum
Head of pancreas
Pancreas/pathology
Duodenal Neoplasms/pathology
Pancreatic Serous Cystic Neoplasm
Pancreaticoduodenectomy
Pathology and Forensic Medicine
Resection
Neoplasms
Multiple Primary
03 medical and health sciences
0302 clinical medicine
Duodenal Neoplasms
Cystadenoma
Serous/diagnostic imaging
Humans
Medicine
Neoplasms
Multiple Primary/pathology
Pancreas
Lymph node
serous cystic neoplasm
Aged
Incidental Findings
neuroendocrine neoplasm
business.industry
Cystadenoma
Serous
Duodenum/pathology
Neuroendocrine Tumors/diagnostic imaging
duodenal tumor
pancreatic cystic tumor
Cystic Neoplasm
Pancreatic Neoplasms
Neuroendocrine Tumors
Serous fluid
Pancreatic Neoplasms/diagnostic imaging
medicine.anatomical_structure
Lymphatic Metastasis
030220 oncology & carcinogenesis
Abdomen
Female
030211 gastroenterology & hepatology
Surgery
Lymph
Radiology
Anatomy
business
Zdroj: Madelung, A B & Detlefsen, S 2018, ' Synchronous Pancreatic Serous Cystic Neoplasm and Duodenal Neuroendocrine Tumor : Case Report and Review of the Literature ', International Journal of Surgical Pathology, vol. 26, no. 6, pp. 551-557 . https://doi.org/10.1177/1066896918766245
ISSN: 1940-2465
1066-8969
DOI: 10.1177/1066896918766245
Popis: Simultaneous presence of pancreatic serous cystic neoplasms and neuroendocrine neoplasms is rare. We present a case with the incidental finding of a duodenal neuroendocrine tumor (NET) with 2 lymph node metastases in a Whipple resection specimen performed to remove a pancreatic cystic neoplasm that postoperatively turned out to represent a serous cystic neoplasm (SCN). The patient was a 75-year-old female. She presented with loss of appetite and weight. Preoperative contrast-enhanced computed tomography scan of the abdomen showed a multicystic lesion in the head of pancreas. On histologic examination of the resection specimen, a pancreatic SCN was found, and in addition in 2 peripancreatic lymph nodes, metastases from a NET. Further examination of the resected specimen revealed a duodenal NET. Review of the literature revealed only one prior study with 4 cases of pancreatic SCN associated with a duodenal NET. In 1 of the 4 cases, the patient had von Hippel-Lindau disease. Our report emphasizes the importance of careful examination of pancreatic resection specimens including the peripancreatic lymph nodes also when dealing with SCNs, as coexisting and more malignant tumors may otherwise be missed.
Databáze: OpenAIRE
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