Electrocorticogram changes during corpus callosotomy for uncontrolled symptomatic generalized epilepsy

Autor: Ji Ho Lin, Chun Hing Yiu, Tai-Tong Wong, Kai Ping Chang, Shang Yeong Kwan, Hann Yeh Shyu
Rok vydání: 2010
Předmět:
Zdroj: Journal of Clinical Neuroscience. 17:132-134
ISSN: 0967-5868
DOI: 10.1016/j.jocn.2009.02.022
Popis: We report a 19-year-old man who presented to our facility with medically intractable, symptomatic generalized epilepsy manifesting as generalized tonic-clonic seizures (GTCs). Before he underwent an anterior callosotomy (6 cm), these seizures, which he had experienced for 11 years, seemed to have a left-sided focal origin. Intraoperatively, no epileptiform discharges were found on the electrocorticogram (ECoG) performed prior to sectioning, but more than 10 left-sided seizures were recorded after sectioning. In the 10 years since surgery, the patient's seizures have remained generalized; however, the frequency and severity of the seizures have decreased. These findings indicate that the presence of electrocorticographic seizures, as measured by ECoG immediately following callosotomy, may not predict a poor surgical outcome, even though such a finding might be indicative of epileptogenicity in general.
Databáze: OpenAIRE