Time-dose relationships in combined bleomycin treatment and radiotherapy
| Autor: | Svend Juul Jørgensen |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Male
Pathology medicine.medical_specialty Time Factors medicine.medical_treatment Biological effect Bleomycin Mice chemistry.chemical_compound Carcinoma medicine Animals Transplantation Homologous Neoplasm Chemotherapy Antibiotics Antineoplastic business.industry Therapeutic effect Radiotherapy Dosage Neoplasms Experimental General Medicine respiratory system medicine.disease respiratory tract diseases carbohydrates (lipids) Radiation therapy Thigh chemistry Toxicity Carcinoma Squamous Cell Cancer research Female business Neoplasm Transplantation |
| Zdroj: | European Journal of Cancer (1965). 8:531-534 |
| ISSN: | 0014-2964 |
| DOI: | 10.1016/0014-2964(72)90105-3 |
| Popis: | The biological effect of bleomycin resembles that of X-ray irradiation indicating that the combination of bleomycin and radiotherapy may have a synergistic effect. In cyclic bleomycin treatment of a murine carcinoma it was found that intermittent bleomycin treatment and radiotherapy results in a simple addition of the therapeutic effects of the two different treatments. Simultaneous treatment, however, results in a synergistic intensifying of the therapeutic effect. The toxicity of bleomycin was found to be unaltered by the regional application of X-ray irradiation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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