Arsenic exposure in a copper smelter as related to histological type of lung cancer

Autor: Victor E. Archer, Marvin Kuschner, Merrill J. Wicks, Oscar Auerbach
Rok vydání: 1981
Předmět:
Zdroj: American Journal of Industrial Medicine. 2:25-31
ISSN: 1097-0274
0271-3586
Popis: Tissue samples from lung cancer patients who had worked at a copper smelter and from controls were collected and classified by a panel of pathologists: 38% of the cancers were found to be adenocarcinomas, compared to 12% among the controls, a statistically significant difference (p less than 0.05). The predominance of adenocarcinomas was associated with arsenic exposure. This finding is not consistent with Kreyberg's hypothesis that small-cell undifferentiated and epidermoid carcinomas are the only type that increase in response to inhaled carcinogens [1962].
Databáze: OpenAIRE