THE ROLE OF PYRIMIDINE DIMERS AND NON-DIMER DAMAGE IN THE INACTIVATION OF ESCHERICHIA COLI BY UV RADIATION

Autor:	S. H. Moss, N. D. M. Hodges, D. J. G. Davies
Rok vydání:	1980
Předmět:	Strain (chemistry) Ultraviolet Rays Chemistry Dimer Pyrimidine dimer General Medicine Radiation medicine.disease_cause Biochemistry chemistry.chemical_compound Pyrimidine Dimers In vivo Mutation Escherichia coli Biophysics medicine Physical and Theoretical Chemistry Triplet state Photolyase
Zdroj:	Photochemistry and Photobiology. 31:571-577
ISSN:	1751-1097 0031-8655
DOI:	10.1111/j.1751-1097.1980.tb03748.x
Popis:	— We have quantitated the role of pyrimidine dimers and non-dimer damage in the inactivation of Escherichia coli by far-UV radiation, near-UV radiation, and triplet state sensitized near-UV radiation. The extent of photoreactivation in vivo of an excision and postreplication repair-deficient strain of E. coli after the different radiation treatments has been correlated with the relative proportion of pyrimidine dimers and non-dimer lesions produced. Using an excision deficient strain of E. coli, the susceptibility to recA+ -dependent repair of the damage produced by the different radiation treatments has also been quantified.
Databáze:	OpenAIRE
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