130 years of Plant Lectin Research
| Autor: | Mariya Tsankova Tsaneva, Els J.M. Van Damme |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Biomedical Research
Glycobiology Carbohydrates Review Article Computational biology Protein-carbohydrate interaction Plant Lectins History 21st Century Biochemistry 03 medical and health sciences Humans Protein–carbohydrate interactions Glycomics Molecular Biology 030304 developmental biology 0303 health sciences biology Biomedical application 030302 biochemistry & molecular biology Lectin History 19th Century Cell Biology History 20th Century Carbohydrate moiety Plant protection biology.protein |
| Zdroj: | Glycoconjugate Journal |
| ISSN: | 1573-4986 0282-0080 |
| DOI: | 10.1007/s10719-020-09942-y |
| Popis: | Lectins are proteins with diverse molecular structures that share the ability to recognize and bind specifically and reversibly to carbohydrate structures without changing the carbohydrate moiety. The history of lectins started with the discovery of ricin about 130 years ago but since then our understanding of lectins has dramatically changed. Over the years the research focus was shifted from 'the characterization of carbohydrate-binding proteins' to 'understanding the biological function of lectins'. Nowadays plant lectins attract a lot of attention especially because of their potential for crop improvement and biomedical research, as well as their application as tools in glycobiology. The present review aims to give an overview of plant lectins and their applications, and how the field evolved in the last decades. |
| Databáze: | OpenAIRE |
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