Role of iron deficiency and anemia in cardio-renal syndromes
| Autor: | Stephan von Haehling, Philipp Attanasio, Mariantonietta Cicoira, Claudio Ronco, Stefan D. Anker |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pediatrics
medicine.medical_specialty Anemia Iron Renal function Ferric Compounds Cardio-Renal Syndrome hemic and lymphatic diseases medicine Humans cardiovascular diseases Iron-Deficiency complications/drug therapy Cardio-Renal Syndrome complications/drug therapy Chronic Disease Erythropoietin therapeutic use Ferric Compounds therapeutic use Hematinics therapeutic use Humans Iron therapeutic use Intensive care medicine Erythropoietin Anemia Iron-Deficiency business.industry Iron deficiency medicine.disease Pathophysiology Nephrology Heart failure Chronic Disease cardiovascular system Hematinics complications/drug therapy business circulatory and respiratory physiology Kidney disease medicine.drug |
| Zdroj: | Seminars in nephrology. 32(1) |
| ISSN: | 1558-4488 |
| Popis: | Chronic heart failure is a common disorder associated with unacceptably high mortality rates. Chronic renal disease and anemia are two important comorbidities that significantly influence morbidity and mortality in patients with chronic heart failure (CHF). Progress in CHF again may cause worsening of kidney function and anemia. To describe this vicious cycle, the term cardio-renal anemia syndrome has been suggested. Iron deficiency is part of the pathophysiology of anemia in both CHF and chronic kidney disease, which makes it an interesting target for treatment of anemia in cardio-renal anemia syndrome. Recently, studies have highlighted the potential clinical benefits of treating iron deficiency in patients with CHF, even if these patients are nonanemic. This article summarizes studies investigating the influence of iron deficiency with or without anemia in chronic kidney disease and CHF and gives an overview of preparations of intravenous iron currently available. |
| Databáze: | OpenAIRE |
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