Chronic viral hepatitis and chronic kidney disease
| Autor: | Elias C Chacko, Soondal Koomar Surrun, T P Mubarack Sani, Joseph M Pappachan |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Hepatitis B virus
medicine.medical_specialty business.industry Mortality rate Hepatitis C virus General Medicine Hepatitis C Hepatitis C Chronic Hepatitis B urologic and male genital diseases medicine.disease medicine.disease_cause Antiviral Agents Virology female genital diseases and pregnancy complications Hepatitis B Chronic Internal medicine Chronic Disease medicine Humans Kidney Diseases Viral disease business Viral hepatitis Kidney disease |
| Zdroj: | Postgraduate Medical Journal. 86:486-492 |
| ISSN: | 1469-0756 0032-5473 |
| DOI: | 10.1136/pgmj.2009.092775 |
| Popis: | Chronic kidney disease (CKD) has become a major public health problem worldwide over the past few decades because of the increasing prevalence of hypertension, diabetes mellitus, and elderly individuals in most countries. Chronic viral hepatitis (due to hepatitis B virus (HBV) and hepatitis C virus (HCV)) also poses significant morbidity and mortality globally. Both these viruses can cause CKD and these infections can occur as a consequence of CKD management. CKD patients acquiring HBV or HCV infection have higher morbidity and mortality rates, and the management of these infections among CKD patients with antiviral agents is associated with high rates of adverse effects. The optimal management of CKD associated with HBV and HCV is not well defined because of insufficient data from clinical trials. This review discusses the pathogenesis, clinical characteristics and management issues related to chronic viral hepatitis and CKD. |
| Databáze: | OpenAIRE |
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