Pharmaceuticals and personal care products in the environment: What are the big questions?

Autor: Jason P. Berninger, Kim Ostapyk, Bryan W. Brooks, Joanne L. Parrott, Roberta Moore, Tim Verslycke, Murray A. Rudd, Anja Coors, Jon F. Ericson, Edward Topp, John P. Giesy, Paul C. DeLeo, Maja V. Karlsson, Elizabeth Innes, Jason Snape, Gerald R. Tetreault, Glen Van Der Kraak, Kyungho Choi, D. G. Joakim Larsson, Silke Hickmann, Scott D. Dyer, Mark E. McMaster, Vance L. Trudeau, James M. Lazorchak, Daniel J. Caldwell, Scott E. Belanger, Jane P. Staveley, Pedro Carriquiriborde, Juerg Oliver Straub, Todd Gouin, Roger D. Meyerhoff, Mark R. Servos, Karen F. Beazley, Alistair B.A. Boxall, Gerald T. Ankley, Lars K Hallstrom, Paul K. Sibley, Alison McLaughlin, Richard Murray-Smith, Frank Mastrocco, François Gagné, Nora D. Szabo
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Prioritization
Drug-Related Side Effects and Adverse Reactions
Antibiotic resistance
Health
Toxicology and Mutagenesis
Biología
Review
Environmental impact of pharmaceuticals and personal care products
Ciencias de la Tierra y relacionadas con el Medio Ambiente
purl.org/becyt/ford/1 [https]
purl.org/becyt/ford/1.5 [https]
Environmental health
Humans
Ecotoxicity
Risk management
Risk assessment
business.industry
Research
Public Health
Environmental and Occupational Health
Household Products
Drug Resistance
Microbial
Environmental Exposure
Environmental exposure
Public relations
Pharmaceutical Preparations
Work (electrical)
Aquatic environment
Personal care products
Exposure assessment
Fish
Pharmaceuticals
Meteorología y Ciencias Atmosféricas
business
CIENCIAS NATURALES Y EXACTAS
Health effects
Environmental Monitoring
Zdroj: Environmental Health Perspectives
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
DOI: 10.1289/ehp.1104477
Popis: Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
Centro de Investigaciones del Medioambiente
Databáze: OpenAIRE
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