Molluscicidal saponins from a Zimbabwean strain of Phytolacca dodecandra
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522cf48bcb767b9812d48e9e5ffc499e https://curis.ku.dk/portal/en/publications/molluscicidal-saponins-from-a-zimbabwean-strain-of-phytolacca-dodecandra(e6f464eb-a80c-4b2a-a4b7-73ec357659f9).html |
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| Rights: | CLOSED |
| Přírůstkové číslo: | edsair.doi.dedup.....522cf48bcb767b9812d48e9e5ffc499e |
| Autor: | S. Brøgger Christensen, Claus Cornett, Else Lemmich, Carl Erik Olsen, Susanne T. Thiilborg |
| Předmět: |
Zimbabwe
Magnetic Resonance Spectroscopy Molluscacides Stereochemistry Molecular Sequence Data Saponin Plant Science Horticulture In Vitro Techniques Biochemistry chemistry.chemical_compound Hemolysin Proteins Triterpene parasitic diseases Animals Molecular Biology Oleanolic acid chemistry.chemical_classification biology Biomphalaria Molecular Structure Glycoside General Medicine Nuclear magnetic resonance spectroscopy Carbon-13 NMR Plants Saponins biology.organism_classification Phytolacca dodecandra carbohydrates (lipids) chemistry Carbohydrate Sequence Molluscicide Cattle |
| Zdroj: | University of Copenhagen |
| Popis: | Three new monodesmosidic saponins, all glycosides of 2 beta-hydroxyoleanolic acid, were isolated from an aqueous extract of a Zimbabwean strain of Phytolacca dodecandra. Their structures were, mainly by spectroscopic methods (LSIMS, 1H NMR, COSY, NOESY, TOCSY, J-resolved 1H NMR, 13C NMR, HETCOR), established as 3-O-[2',4'-di-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid, 3-O-[O-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl- (1-->3)]-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid and 3-O-[3'-O-(beta-D-galactopyranosyl)-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid. Two of the saponins were submitted to a preliminary screening for molluscicidal activity against the schistosomiasis transmitting snail Biomphalaria glabrata and showed, respectively, strong and weak activity. In addition, four saponins previously reported from other strains of Phytolacca dodecandra were identified. |
| Databáze: | OpenAIRE |
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