| Autor: |
Boyagoda Vidanelage Loshini Ravima Ranaweera, Daniya Edward, Ajita Mahendra Abeysekera, Ovitigala Vithanage Don Sisira Jagathpriya Weerasena, Shiroma Mangalika Handunnetti |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 2, Pp 100528-(2022) |
| ISSN: |
0975-9476 |
| Popis: |
Background: Link Samahan® (LS) is a standardized modern formulation of a polyherbal preparation used in the indigenous system of medicine in Sri Lanka. Objective: Evaluation of the immunostimulatory activity of LS and the molecular mechanisms that modulate the humoral immune response. Material and methods: Immunostimulatory activity of LS was tested in rats following oral administration on days 1-5 and 15-19 and immunization with bovine serum albumin (BSA) on day 1 and 15. Anti-BSA IgM and IgG response in rats treated with LS, water and sugar (as controls) were compared on days 0-35, using ELISA. The expression of co-stimulatory molecules on lymphocytes was assessed on days 0-8 and days 14-22 using RT-qPCR. Results: IgM and IgG levels of LS-treated rats were increased significantly by day 7 and 21 respectively compared to controls (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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