Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes
| Autor: | Richard A. Mueller, J. V. N. Vara Prasad, Garland R. Marshall, Mihaly V. Toth, Chong Qing Sun, Ahammadunny Pathiasseril, Daniel H. Rich, Michael Clare, Kathryn Houseman |
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| Rok vydání: | 1991 |
| Předmět: |
Chemical Phenomena
Stereochemistry medicine.medical_treatment Molecular Sequence Data Molecular Conformation Peptide Stereoisomerism Structure-Activity Relationship chemistry.chemical_compound HIV Protease Drug Discovery medicine HIV Protease Inhibitor Structure–activity relationship Amino Acid Sequence chemistry.chemical_classification Oligopeptide Protease Dipeptide Molecular Structure biology Hydrogen Bonding Dipeptides HIV Protease Inhibitors Chemistry chemistry Ethanolamines Enzyme inhibitor biology.protein Molecular Medicine |
| Zdroj: | Journal of Medicinal Chemistry. 34:1222-1225 |
| ISSN: | 1520-4804 0022-2623 |
| DOI: | 10.1021/jm00107a049 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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