Mediastinal lymphadenopathy may predict 30-day mortality in patients with COVID-19

Autor: Elif Sargin Altunok, Mustafa Asim Demirkol, Sinem Nihal Esatoglu, Celal Satici, Ferhat Cengel, Okan Gurkan
Rok vydání: 2021
Předmět:
Adult
medicine.medical_specialty
PSI
pneumonia severity index
Mediastinal lymphadenopathy
Coronavirus disease 2019 (COVID-19)
DBP
diastolic blood pressure
Lymphadenopathy
Logistic regression
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine
IPF
idiopathic pulmonary fibrosis
Humans
Radiology
Nuclear Medicine and imaging
In patient
Cardiothoracic Imaging
Mortality
COVID-19
coronavirus disease 2019
Aged
Retrospective Studies
SARS-CoV-2
business.industry
SBP
systolic blood pressure
Medical record
COVID-19
Radiological findings
medicine.disease
Comorbidity
PCT
procalcitonin
CT
computed tomography
Cross-Sectional Studies
COPD
chronic obstructive pulmonary disease
Radiology Nuclear Medicine and imaging
30 day mortality
030220 oncology & carcinogenesis
Radiology
business
Large group
CRP
C-reactive protein levels
Zdroj: Clinical Imaging
ISSN: 0899-7071
Popis: Purpose There is scarce data on the impact of the presence of mediastinal lymphadenopathy on the prognosis of coronavirus-disease 2019 (COVID-19). We aimed to investigate whether its presence is associated with increased risk for 30-day mortality in a large group of patients with COVID-19. Method In this retrospective cross-sectional study, 650 adult laboratory-confirmed hospitalized COVID-19 patients were included. Patients with comorbidities that may cause enlarged mediastinal lymphadenopathy were excluded. Demographics, clinical characteristics, vital and laboratory findings, and outcome were obtained from electronic medical records. Computed tomography scans were evaluated by two blinded radiologists. Univariate and multivariate logistic regression analyses were performed to determine independent predictive factors of 30-day mortality. Results Patients with enlarged mediastinal lymphadenopathy (n = 60, 9.2%) were older and more likely to have at least one comorbidity than patients without enlarged mediastinal lymphadenopathy (p = 0.03, p = 0.003). There were more deaths in patients with enlarged mediastinal lymphadenopathy than in those without (11/60 vs 45/590, p = 0.01). Older age (OR:3.74, 95% CI: 2.06–6.79; p
Databáze: OpenAIRE
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