A rare case of regressively changed lipomatous hypertrophy of the interatrial septum presenting with anemia and recurrent fever

Autor: David Zogala, Aleš Linhart, Tomas Palecek, Vladimir Cerny, Martin Masek, Eduard Nemecek, Ivana Vitkova, Zuzana Rucklova, Daniel Rob, Petr Kuchynka
Rok vydání: 2016
Předmět:
Zdroj: Cardiovascular Pathology. 25:161-164
ISSN: 1054-8807
DOI: 10.1016/j.carpath.2015.09.002
Popis: Lipomatous hypertrophy of the interatrial septum (LHIS) is characterized by excessive accumulation of adipose tissue within some segments of the interatrial septum. Only one published case so far describes fever as a presenting feature of LHIS. On the other hand, systemic symptoms including anemia and fever are well-known clinical presentations of cardiac myxomas. We report an unusual case of a 79-year-old woman who was thoroughly but unsuccessfully investigated for recurrent fever and anemia in several specialized departments over the course of 4 years. Computed tomography scan showed a pathological mass localized in the interatrial septum and spreading to ascending aorta. Histological analysis of the biopsy samples from surgery revealed the unexpected diagnosis of regressively changed LHIS. We discuss the clinical and pathologic features of this lesion suggesting that its regressive changes may be associated with inflammation and can cause systemic symptoms such as fever and anemia.
Databáze: OpenAIRE