Impact of frailty on hospital adverse outcomes in elderly admitted with acute coronary syndrome
| Autor: | F Montenegro Sa, Ana Ponciano, José P. Leite, Fátima Saraiva, João Morais, F. Soares |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome lcsh:Internal medicine Multivariate analysis Adverse outcomes lcsh:Medicine 030204 cardiovascular system & hematology prognostico 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Clinical endpoint 030212 general & internal medicine sindrome coronario agudo lcsh:RC31-1245 Stroke anciano business.industry lcsh:R fragilidad Retrospective cohort study medicine.disease Observational study business TIMI |
| Zdroj: | Galicia Clínica, Vol Vol, Iss Num, Pp 4-7 (2020) |
| ISSN: | 1989-3922 0304-4866 |
| Popis: | Background: Frailty represents a complex clinical syndrome of decreased physiological reserve and increased vulnerability to stressors. Little is known regarding interaction between frailty status and outcomes in patients with acute coronary syndrome. Our study aims to assess the prevalence of frailty and its impact on in-hospital adverse outcomes of patients aged ≥ 75 years admitted for acute coronary syndromes. Methods: In this retrospective, single centre, observational study were included patients aged ≥ 75 years admitted for acute coronary syndromes between January 2011 and December 2015. Frailty was assessed using the Fried criteria. The primary endpoint was all-cause in-hospital mortality. Secondary endpoints included the occurrence of re-infarction, stroke and major bleeding. Results: Of the 502 patients included, 126 were classified as frail. These patients were older (mean age 78±5.5 vs. 76.2±5.5 years; p=0.02), more often male (68.3%) and had a higher risk profile according to GRACE (151.4±18.8 vs. 132.1±16.8; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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