Can the emotional connotation of concepts modulate the lexico-semantic deficits in Alzheimer's disease? : Emotion and semantic memory in Alzheimer's disease
| Autor: | Francis Eustache, Bénédicte Giffard, Mickaël Laisney, Béatrice Desgranges |
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| Přispěvatelé: | Neuropsychologie cognitive et neuroanatomie fonctionnelles de la mémoire humaine, Université de Caen Normandie ( UNICAEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -École pratique des hautes études ( EPHE ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) |
| Rok vydání: | 2009 |
| Předmět: |
Male
Emotions MESH : Aged MESH : Alzheimer Disease MESH : Analysis of Variance Neuropsychological Tests Behavioral Neuroscience Mental Processes 0302 clinical medicine Semantic memory MESH : Female MESH : Semantics computer.programming_language Aged 80 and over 05 social sciences Cognition MESH : Language Disorders Semantics MESH : Neuropsychological Tests Connotation (semiotics) Female Lexico Psychology Priming (psychology) Cognitive psychology MESH : Case-Control Studies MESH : Male MESH : Mental Processes Cognitive Neuroscience Decision Making Experimental and Cognitive Psychology Affect (psychology) MESH : Emotions 050105 experimental psychology 03 medical and health sciences Alzheimer Disease Similarity (psychology) Lexical decision task Humans 0501 psychology and cognitive sciences MESH : Aged 80 and over Aged Analysis of Variance Language Disorders MESH : Humans MESH : Decision Making Case-Control Studies [ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] computer 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychologia Neuropsychologia, Elsevier, 2009, 47 (1), pp.258-67. 〈10.1016/j.neuropsychologia.2008.07.013〉 |
| ISSN: | 0028-3932 |
| DOI: | 10.1016/j.neuropsychologia.2008.07.013 |
| Popis: | International audience; Semantic memory impairments are a common symptom of Alzheimer's disease (AD) and may occur at a relatively early stage. These disturbances can be evidenced by a hyperpriming effect (greater semantic priming in AD patients than in controls). Up till now, very few studies of semantic memory have included emotionally charged concepts. Our aim was therefore to study the semantic processing of such concepts, as opposed to neutral ones, in early AD. Given that emotional processes are relatively preserved at the beginning of the disease compared with other cognitive functions, we expected that an emotional connotation would influence the spreading activation of words and affect some of the impairments in semantic processing. We administered a semantic priming task (lexical decision task) implicitly assessing semantic memory to 26 patients with AD and 26 normal controls. Primes and targets either had a semantic relationship (e.g. tiger-lion), a semantic and emotional (positive or negative) relationship (e.g. slap-smack) or no relationship at all (e.g. chair-horse), or else belonged to a word-nonword condition (e.g. window-inuly). Compared with controls, the patients showed pathological hyperpriming effects in all conditions, especially in the emotional conditions. Hyperpriming implies a deterioration in specific attributes, as it is difficult to tell two concepts apart once their distinctive attributes have been lost. These results suggest that emotional concepts, like neutral ones, lose some of their distinctive attributes in early AD, and as the emotional processes are preserved, there is greater similarity between close emotional concepts than between close neutral concepts. |
| Databáze: | OpenAIRE |
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