Retraction: Oral leukoplakia, a clinical-histopathological study in 412 patients
Autor: | Andrea Rubert, Jose V Bagán, Leticia Bagan |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Epithelial dysplasia
medicine.medical_specialty Oral Medicine and Pathology business.industry Research 030206 dentistry Disease Dermatology Malignant transformation Lesion Oral leukoplakia 030207 dermatology & venereal diseases 03 medical and health sciences stomatognathic diseases 0302 clinical medicine medicine.anatomical_structure Tongue Homogeneous medicine medicine.symptom Stage (cooking) business General Dentistry UNESCO:CIENCIAS MÉDICAS |
Zdroj: | Journal of Clinical and Experimental Dentistry Rubert, A., Bagán, L., & Bagán, J. V. (2021). Retraction: Oral leukoplakia, a clinical-histopathological study in 412 patients. Journal of clinical and experimental dentistry, 13(5), e426–e432. |
ISSN: | 1989-5488 |
Popis: | The authors detected some minor errors in the published manuscript (Rubert A, Bagan L, Bagan JV. Oral leukoplakia, a clinical-histopathological study in 412 patients. J Clin Exp Dent. 2020 Jun 1;12(6):e540-e546. doi: 10.4317/jced.57091. PMID: 32665812; PMCID: PMC7335600.) and have requested that the entire article be republished with these errors already rectified. Background A retrospective clinical-histopathological study was made of the evolution of oral leukoplakia over time, staging the disease according to the classification of van der Waal. Material and methods A study was made of 412 patients with oral leukoplakia, analyzing the corresponding clinical factors and histopathological findings; assessing associations between the different clinical presentations and epithelial dysplasia; and evaluating the factors influencing malignant transformation of the lesions. Results Clinically, homogeneous presentations were seen to predominate (n = 336, 81.6%), while histologically most of the lesions exhibited no dysplastic changes (n = 271; 65.7%). Stage 1 of the van der Waal classification was the most common presentation (n = 214; 51.9%). The lesion malignization rate was 8.5%, and the factors associated to a significantly increased malignization risk were non-homogeneous OL lesions (p=0.00), lesion location in the tongue (p=0.00), and the presence of epithelial dysplasia (p=0.00). Conclusions In our series of patients with oral leukoplakia, malignization was associated to the less common clinical presentations of the disease, i.e., non-homogeneous lesions, and the latter tended to exhibit high grade epithelial dysplasia. Key words:Oral leukoplakia, potentially malignant disorders, malignant transformation. |
Databáze: | OpenAIRE |
Externí odkaz: |