Effect of dairy and nondairy snacks on postprandial blood glucose regulation in 9–14-year-old children
| Autor: | Brandon Gheller, G. Harvey Anderson, Bohdan L. Luhovyy, Fernando Nunes, Athena Li, Younes Anini, Theresa Glanville, Jill Hamilton, Mary E Gheller, Nick Bellissimo |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Adolescent 030309 nutrition & dietetics Physiology Endocrinology Diabetes and Metabolism medicine.medical_treatment Appetite 030209 endocrinology & metabolism 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Glucagon-Like Peptide 1 Physiology (medical) Internal medicine medicine Humans Insulin Obesity Child 0303 health sciences Cross-Over Studies Nutrition and Dietetics C-Peptide Snacking C-peptide business.industry digestive oral and skin physiology General Medicine Overweight Postprandial Period medicine.disease Endocrinology Postprandial Liver chemistry Female Blood sugar regulation Dairy Products Snacks business |
| Zdroj: | Applied Physiology, Nutrition, and Metabolism. 44:1073-1080 |
| ISSN: | 1715-5320 1715-5312 |
| DOI: | 10.1139/apnm-2018-0549 |
| Popis: | In adults, dairy consumption improves short-term blood glucose regulation. It is unknown if these short-term benefits extend to children of different weight statuses. The objective of this study was to investigate the effect of a dairy and nondairy snack in both normal-weight (NW) and overweight/obese (OW/OB) children on blood glucose regulation and food intake (FI). In a repeated-measures crossover design, 11 NW and 7 OW/OB children (age: 9–14 years), consumed, in random order, a dairy (Greek yogurt, 198.9 g, 171 kcal, 0 g fat, 17 g protein) or nondairy (mini sandwich-type cookies, 37.5 g, 175 kcal, 7.5 g fat, 1.3 g protein) snack containing 25 g of available carbohydrates. Ad libitum FI was measured 120 min after snack consumption. Blood glucose, insulin, C-peptide, and glucagon-like peptide-1 (GLP-1) were measured at 0 min (before the snack), and at 30, 60, 90, and 120 min after snack consumption. Insulin secretion was calculated from deconvolution of C-peptide. Hepatic insulin extraction was calculated as C-peptide divided by insulin. FI did not differ between snacks (P = 0.55). Mean blood glucose was lower (P < 0.001) and insulin higher (P < 0.0001) in the 120 min after consuming the dairy snack. C-Peptide concentrations (P = 0.75) and insulin secretion (P = 0.37) were not different between snacks. The increase in insulin was explained by reduced hepatic insulin extraction (P < 0.01). Consumption of the dairy snack also increased mean GLP-1 concentrations (P < 0.001). In conclusion, consumption of a dairy snack by NW and OW/OB children results in reduced postprandial blood glucose concentrations and elevated circulating insulin compared with a nondairy snack possibly because of delayed hepatic insulin extraction. |
| Databáze: | OpenAIRE |
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