Atypical Hemolytic and Uremic Syndrome Triggered by Infection With SARS-CoV2
Autor: | Hermann Haller, Martin Reinhardt, Akel Khaled, Bernhard M W Schmidt, Christoph Schröder, Jessica Kaufeld, Jan Hinrich Bräsen, Anja Gäckler, Thorsten Wiech, Carsten Bergmann, Philipp Brylka |
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Rok vydání: | 2021 |
Předmět: |
Kidney
2019-20 coronavirus outbreak Thrombotic microangiopathy business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Medizin urologic and male genital diseases medicine.disease Thrombosis Hemolysis Complement system Endothelial stem cell medicine.anatomical_structure Nephrology hemic and lymphatic diseases Immunology Medicine business |
Zdroj: | Kidney International Reports. 6:2709-2712 |
ISSN: | 2468-0249 |
Popis: | Atypical hemolytic and uremic syndrome (aHUS), as a form of thrombotic microangiopathy, (TMA) is characterized by a genetic or acquired dysregulation of complement activation, leading to endothelial cell lesions and thrombosis of the small vessels, hemolysis, thrombocytopenia, and acute kidney injury.S1 Here, we report 2 cases of complement mediated aHUS triggered by infection with SARS-CoV-2. |
Databáze: | OpenAIRE |
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