Drug interaction leading to prolonged sedation in a postoperative high risk coronary bypass surgery patient

Autor: Jitesh Chauhan, Vinay Kulkarni, Saurabh Barde, Sudhir Dhumne, Shrikant Bobade, Avinash Sharma
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
ISSN: 1998-359X
0972-5229
Popis: Use of midazolam infusion in mechanically ventilated patient is an established practice in critical care. In our case, the use of erythromycin as a prokinetic agent for better tolerance of enteral feeding and paralytic ileus led to an interaction between midazolam and erythromycin, which resulted in prolonged and deeply sedated patient. In a critically ill patient, there is always a possibility of multiple drug interactions. It is important to understand them and they should be considered before starting new medication.
Databáze: OpenAIRE