Drug interaction leading to prolonged sedation in a postoperative high risk coronary bypass surgery patient
Autor: | Jitesh Chauhan, Vinay Kulkarni, Saurabh Barde, Sudhir Dhumne, Shrikant Bobade, Avinash Sharma |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Drug
medicine.medical_specialty business.industry media_common.quotation_subject Sedation medicine.medical_treatment Prokinetic agent Erythromycin Case Report Drug interaction Critical Care and Intensive Care Medicine Enteral administration Bypass surgery midazolam Anesthesia medicine Midazolam medicine.symptom business Intensive care medicine prolonged sedation media_common medicine.drug |
Zdroj: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
ISSN: | 1998-359X 0972-5229 |
Popis: | Use of midazolam infusion in mechanically ventilated patient is an established practice in critical care. In our case, the use of erythromycin as a prokinetic agent for better tolerance of enteral feeding and paralytic ileus led to an interaction between midazolam and erythromycin, which resulted in prolonged and deeply sedated patient. In a critically ill patient, there is always a possibility of multiple drug interactions. It is important to understand them and they should be considered before starting new medication. |
Databáze: | OpenAIRE |
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