Neurocognitive and Motor Functions in Biliary Atresia Patients: A Cross-sectional, Prospective National Cohort Study
| Autor: | Mikko Lähteenmäki, Taru Häyrinen, Timo Jahnukainen, Satu Ruuska, Kaisa Kanerva, Mikko P. Pakarinen, Leena Haataja, Kaija-Leena Kolho |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Adolescent medicine.medical_treatment Portoenterostomy Hepatic Liver transplantation National cohort Cohort Studies 03 medical and health sciences Liver disease Young Adult 0302 clinical medicine Biliary atresia Biliary Atresia 030225 pediatrics Medicine Humans Prospective Studies Child Motor skill Intelligence quotient business.industry Gastroenterology Infant Jaundice medicine.disease 3. Good health Cross-Sectional Studies Child Preschool Pediatrics Perinatology and Child Health 030211 gastroenterology & hepatology medicine.symptom business Neurocognitive |
| Zdroj: | Journal of pediatric gastroenterology and nutrition. 73(4) |
| ISSN: | 1536-4801 |
| Popis: | OBJECTIVES The aim of the study was to evaluate the neurocognitive and motor development of biliary atresia (BA) patients in childhood and adolescence and to identify risk factors for impaired outcome. METHODS We invited all BA patients between ages 1 and 20 years followed up at Helsinki University Children's Hospital in Finland between 1 January 2019 to 31 January 2020 to participate. All participants underwent age-appropriate validated neurocognitive tests. Participants between 3.0 and 16.9 years of age were assessed with the Movement Assessment Battery for children, version 2. Guardians of participants between ages 5 and 17 years filled the Five-to-Fifteen-Revised (5-15R) parental questionnaire. RESULTS The mean (±standard deviation [SD]) total intelligence quotient (IQ) of the 39 participants was 91 ± 15, lower compared with test norms (mean IQ 100 ± 15, P |
| Databáze: | OpenAIRE |
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