Open-irrigated laser catheter ablation: influence of catheter-tissue contact force on lesion formation
| Autor: | Michaela Sagerer-Gerhardt, Helmut P. Weber |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Heart Ventricles Catheter ablation Lasers Solid-State Sensitivity and Specificity law.invention Contact force Lesion law Physiology (medical) Internal medicine medicine Pressure Animals Thrombus Therapeutic Irrigation Laser ablation business.industry Myocardium Thrombosis Laser Ablation medicine.disease Catheter Models Animal Cardiology Catheter Ablation Cattle Laser Therapy medicine.symptom Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Zdroj: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 42(2) |
| ISSN: | 1572-8595 |
| Popis: | Purpose Catheter–tissue contact force (CF) is a major determinant for radiofrequency (RF) ablation lesion size and quality. We sought to test the influence of catheter CF on lesion formation by using an open-irrigated electrode-laser mapping and ablation (ELMA) catheter. Methods With the ELMA catheter in a stable vertical position, continuous wave 1064 nm laser impacts at 15 W (9.5 W/mm 2 ), 30 s (285 J/mm 2 ), irrigation flow 30 mL/min, were aimed at the endocardial surface of bovine myocardium in heparinized stagnant blood (ACT >350 s) at room temperature (18 °C). Lesions were produced with CFs of 100 g, 10 g, in contact but without pressure, with the catheter tip 2.0 mm, and 5.0 mm away (n=10, each). Lesions were evaluated morphometrically and were compared by the unpaired t tests. Results There were no significant differences between volumes of lesions achieved with catheter–tissue CF of 100 g, 10 g, and in contact without pressure: 297±56.0vs.300± 39 vs. 320±24, respectively (p>0.05). However, volumes of lesions produced at a distance of 2 mm (95±14 mm 3 )w ere significantly smaller (p |
| Databáze: | OpenAIRE |
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