The effect of hemodialysis on intraocular pressure
| Autor: | Nurgul Guven, Ayse Ebru Kilavuzoglu, Savas Marsap, Gurkan Yurteri, Ali Riza Cenk Celebi, Cemile Banu Cosar |
|---|---|
| Přispěvatelé: | Acibadem University Dspace |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Intraocular pressure genetic structures medicine.medical_treatment 030232 urology & nephrology Urology Diastole Medicine (miscellaneous) Glaucoma Blood Pressure 030204 cardiovascular system & hematology Hematocrit General Biochemistry Genetics and Molecular Biology Tonometry Ocular 03 medical and health sciences 0302 clinical medicine Renal Dialysis Internal Medicine medicine Humans Arterial Pressure Pharmacology (medical) Prospective Studies Blood urea nitrogen Genetics (clinical) Aged Aged 80 and over Osmole hemodialysis medicine.diagnostic_test business.industry Middle Aged medicine.disease eye diseases glaucoma Reviews and References (medical) Kidney Failure Chronic Female Ocular Hypertension sense organs Hemodialysis business Perfusion intraocular pressure |
| Popis: | BACKGROUND The effect of hemodialysis (HD) on intraocular pressure (IOP) has been investigated before, but there is a lack of consensus. Clinicians dealing with renal failure patients are interested in the potential negative effects of HD on IOP and the course of glaucoma. OBJECTIVES The aim of this study was to investigate the effects of HD on IOP in patients with end-stage renal disease. MATERIAL AND METHODS This prospective study included 106 patients who were receiving outpatient hemodialysis. Patient history of systemic and ophthalmologic conditions was recorded. Serum osmolality (mOsm), blood urea nitrogen (BUN), blood glucose (BG), bicarbonate (BC), and hematocrit (Hct) levels at the start of HD (pre-HD), at the end of HD (end-HD), and 30 min after HD (post-HD) were measured. Systolic and diastolic blood pressures (SBP and DBP) and IOP were measured at pre-HD, 1-hour intervals during HD, end-HD, and post-HD. RESULTS A significant decrease in mOsm and BUN and a significant increase in BG, BC, and Hct levels were observed at end-HD (p < 0.05). Mean IOP was 16.71 ±2.51 mm Hg at pre-HD, 15.52 ±3.18 mm Hg at endHD, and 15.23 ±2.73 mm Hg at post-HD (p = 0.001; F = 4.439). Post-HD SBP and DBP were significantly lower than at pre-HD (p < 0.001). There was a positive correlation between the change in IOP and the change in mOsm and the change in BUN at end-HD (r = 0.315, p = 0.004; and r = 0.279, p = 0.012, respectively). CONCLUSIONS IOP decreased significantly during HD in this study. Additional research on the effects of the change in blood parameters and ocular perfusion pressure on IOP and optic nerve perfusion during HD is recommended. |
| Databáze: | OpenAIRE |
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