Impairment of respiratory rhythmogenesis and sequelae of bacterial meningitis
| Autor: | Masayuki Shimohira, Takeshi Hasegawa, Jun Kohyama, Yoshihide Iwakawa, Toshihiko Kohji |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
Pathology medicine.medical_specialty Sneeze Developmental Neuroscience medicine Humans Respiratory function Respiratory system Child Medulla Slow-wave sleep Medulla Oblongata Respiratory distress Meningitis Pneumococcal business.industry Respiratory disease medicine.disease Neurology Anesthesia Pediatrics Perinatology and Child Health Respiratory Mechanics Neurology (clinical) medicine.symptom business Meningitis |
| Zdroj: | Pediatric Neurology. 12:357-360 |
| ISSN: | 0887-8994 |
| DOI: | 10.1016/0887-8994(95)00051-g |
| Popis: | A 9-year-old boy with respiratory disturbance associated with medullary lesions after pneumococcal meningitis is reported. Although he lives a normal daily life, he cannot cough or sneeze. A polysomnographic study revealed a low respiration rate and an irregular respiratory rhythm not only during REM sleep but also during slow wave sleep, and marked desaturation during sleep. Respiratory function tests including CO2 response revealed normal values. Magnetic resonance imaging demonstrated bilateral small lesions in the medulla. This patient is unusual because respiratory rhythm is impaired, without decreased ventilatory capacity or CO2 response, supporting the possibility that rhythmogenetic respiratory neurons are located in a limited area of the human medulla. |
| Databáze: | OpenAIRE |
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